کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6117240 | 1217176 | 2014 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
The activation of the adaptive immune system: Cross-talk between antigen-presenting cells, T cells and B cells
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
ایمونولوژی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: The activation of the adaptive immune system: Cross-talk between antigen-presenting cells, T cells and B cells The activation of the adaptive immune system: Cross-talk between antigen-presenting cells, T cells and B cells](/preview/png/6117240.png)
چکیده انگلیسی
The adaptive immune system consists of T and B cells that express clonally distributed antigen receptors. To achieve functional adaptive immune responses, antigen-specific T cell populations are stimulated by professional antigen-presenting cells like dendritic cells (DCs), which provide crucial stimulatory signals for efficient expansion and development of effector functions. Antigen-specific B cells receive costimulatory signals from helper T cells to stimulate affinity maturation and isotype switching. Here we elaborate on the interactions between DCs, T cells and B cells, and on the important signals for efficient induction of adaptive immune responses.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Immunology Letters - Volume 162, Issue 2, Part B, December 2014, Pages 103-112
Journal: Immunology Letters - Volume 162, Issue 2, Part B, December 2014, Pages 103-112
نویسندگان
Joke M.M. den Haan, Ramon Arens, Menno C. van Zelm,