Graphene oxide-Cu(II) composite electrode for non-enzymatic determination of hydrogen peroxide

• A novel graphene oxide-Cu (II) composite material was explored for electrochemical determination of hydrogen peroxide (H2O2) in neutral buffer solution (pH = 7.4).
• The electrode material was synthesized by simple mixing of pH adjusted GO and copper sulphate solution.
• The synthesized material was characterized by XRD and cyclic voltammetry, surface morphology was observed by SEM and AFM and the elemental analysis was performed using EDS.
• The detection limit obtained for this electrode is 0.5 μM with a sensitivity 0.072 μA μM-1 and linear response range from 5 μM to 85 μM (correlation co-efficient = 0.999).

We report a novel graphene oxide-Cu(II) (GO-Cu2 +) composite electrode for electrochemical determination of hydrogen peroxide (H2O2) in neutral solution (pH = 7.4). Oxygen functional groups such as carboxylic acid, hydroxyl and epoxy present on GO are utilized for the formation of composite with Cu2 + ions. The synthesized GO-Cu2 + composite was characterized by X-ray diffraction (XRD) studies and cyclic voltammetry (CV). The surface morphology of the GO and GO-Cu2 + composite materials was observed by scanning electron microscopy (SEM) and atomic force microscopy (AFM). Elemental analysis was performed using EDS. The prepared electrode showed a good electrocatalytic performance for reduction of H2O2 and mechanistic pathway has been discussed. Amperometric determination for H2O2 was carried out at a applied potential of − 0.25 V vs Ag/AgCl and the result showed a linear response range of 5 μM to 85 μM (correlation coefficient = 0.999) with a detection limit of 0.5 μM (S/N = 3). The sensitivity of the electrode was found to be 0.072 μA μM− 1 and the electrode selectively detected H2O2 in the presence of other potential interferences such as oxygen, glucose, ascorbic acid (AA), dopamine (DA) and uric acid (UA).

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