کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
218108 | 463183 | 2016 | 12 صفحه PDF | دانلود رایگان |
• Optimization condition of experiment such as pH, accumulation time and accumulation potential
• Behavior of ITZ at different electrodes
• Suggested mechanism of ITZ
• Differential pulse voltammetry used to perform a calibration curve
• Square wave voltammetry used to perform a calibration curve
• Application to pharmaceutical dosage forms and biological fluids
• Validation of the results
The oxidation of itraconazole at three different electrodes; ultra-trace graphite (UTGE), pencil graphite (PGE) and carbon paste (CPE) electrodes were studied voltammetrically. After the optimization of solution pH, accumulation potential and accumulation time, anodic stripping differential pulse and anodic stripping square wave voltammetric peaks were obtained. The oxidation mechanism was proposed. Based on these findings, a simple and not time-consuming procedure was successfully applied for the determination of itraconazole in pharmaceutics and biological fluids.
The electrochemical behavior of itraconazole at an ultra-trace graphite electrode.Figure optionsDownload as PowerPoint slide
Journal: Journal of Electroanalytical Chemistry - Volume 763, 15 February 2016, Pages 51–62