کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2182565 | 1095471 | 2006 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Characterization of retinoid-X receptor genes rxra, rxrba, rxrbb and rxrg during zebrafish development
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
بیولوژی سلول
پیش نمایش صفحه اول مقاله

چکیده انگلیسی
During development of vertebrate embryos, retinoic acid plays a variety of roles that are mediated by binding to retinoic acid receptors (Rars) and their heterodimerization partners, the retinoid receptors (Rxrs). Here, we characterize the expression patterns of four zebrafish rxr genes during development and provide an analysis of the phylogenetic relationships between zebrafish and tetrapod Rxr genes based on sequence similarities and conserved syntenies. This analysis prompted the renaming of several of the zebrafish rxr genes to match their tetrapod orthologs. Understanding phylogenetic relationships among Rxr genes and their expression patterns during development provides a foundation for future studies of Rxr functions.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Gene Expression Patterns - Volume 6, Issue 5, June 2006, Pages 556–565
Journal: Gene Expression Patterns - Volume 6, Issue 5, June 2006, Pages 556–565
نویسندگان
Alexandra Tallafuss, Laura A. Hale, Yi-Lin Yan, Leana Dudley, Judith S. Eisen, John H. Postlethwait,