کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2191108 1097847 2009 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Morphological dynamics of mitochondria — A special emphasis on cardiac muscle cells
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیولوژی سلول
پیش نمایش صفحه اول مقاله
Morphological dynamics of mitochondria — A special emphasis on cardiac muscle cells
چکیده انگلیسی

Mitochondria play a critical role in cellular energy metabolism, Ca2+ homeostasis, reactive oxygen species generation, apoptosis, aging, and development. Many recent publications have shown that a continuous balance of fusion and fission of these organelles is important in maintaining their proper function. Therefore, there is a steep correlation between the form and function of mitochondria. Many major proteins involved in mitochondrial fusion and fission have been identified in different cell types, including heart. However, the functional role of mitochondrial dynamics in the heart remains, for the most part, unexplored. In this review we will cover the recent field of mitochondrial dynamics and its physiological and pathological implications, with a particular emphasis on the experimental and theoretical basis of mitochondrial dynamics in the heart.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Molecular and Cellular Cardiology - Volume 46, Issue 6, June 2009, Pages 811–820
نویسندگان
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