کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
219295 463258 2012 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Determination of acetazolamide by graphene paste electrode
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی مهندسی شیمی (عمومی)
پیش نمایش صفحه اول مقاله
Determination of acetazolamide by graphene paste electrode
چکیده انگلیسی

Graphene is ideally suited for implementation in electrochemical applications due to its reported large electrical conductivity, large surface area, unique heterogeneous electron transfer rate, and low production cost. This paper presents a method for the construction of graphene paste electrode (GPE) from reduced graphene oxide (RGO). Direct electrochemical detection of drug is of high importance in analytical chemistry. Here, the GPE was successfully used for the determination of acetazolamide (ACZ). So, the influence of some experimental variables such as working solution pH, supporting electrolyte, scan rate, pulse amplitude, and possible interferences were studied. The proposed sensor exhibited a high sensitivity and good selectivity, and it was applied for clinical evaluation of ACZ.

Figure optionsDownload as PowerPoint slideHighlights
► Electroreduction mechanism of ACZ was investigated for the first time.
► Present study describes selective and sensitive procedure to determine ACZ.
► This sensor was applied for clinical evaluation of ACZ.
► This sensitive sensor has nearly wide dynamic range and low LOD.
► The procedure was simple and fast.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Electroanalytical Chemistry - Volume 683, 1 September 2012, Pages 119–124
نویسندگان
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