کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
22129 43255 2007 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Possible Role of Extracellular Signal-Regulated Kinase Pathway in Regulation of Sox9 mRNA Expression in Chondrocytes under Hydrostatic Pressure
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی بیو مهندسی (مهندسی زیستی)
پیش نمایش صفحه اول مقاله
Possible Role of Extracellular Signal-Regulated Kinase Pathway in Regulation of Sox9 mRNA Expression in Chondrocytes under Hydrostatic Pressure
چکیده انگلیسی

The potential involvement of the extracellular signal-regulated kinase (ERK) pathway in chondrocyte mechanotransduction was tested in bovine chondrocyte-agarose constructs under hydrostatic loading. Results suggested that the ERK pathway may be inhibited by hydrostatic pressure-induced mechanotransduction and may also be a negative regulator of Sox9 mRNA expression, which is an important modulator of chondrocyte function.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Bioscience and Bioengineering - Volume 104, Issue 6, December 2007, Pages 506–509
نویسندگان
, , ,