کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2401012 1402274 2016 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Point of Care Measurement of Lactate
ترجمه فارسی عنوان
اندازه گیری نقطه مراقبت از لاکتات
کلمات کلیدی
لاکتات. hyperlactatemia؛ اسید لاکتیک؛ اسیدوز؛ آنیون گپ بالا؛ نقطه مراقبت
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم دامی و جانورشناسی
چکیده انگلیسی

Lactate is generated as a consequence of anaerobic glycolysis by all tissues of the body. Increased l-lactate, the isoform produced by most mammals, reflects increased anaerobic metabolism secondary to tissue hypoperfusion or tissue hypoxia in most clinical situations, and is called type A lactic acidosis. The utility of lactate measurement and serial lactate monitoring in veterinary patients has been demonstrated in multiple studies. Blood lactate concentration is significantly elevated in many disease processes including septic peritonitis, immune-mediated hemolytic anemia, Babesiosis, trauma, gastric dilation and volvulus, and intracranial disease. Lactate clearance can be used to assess response to fluid therapy, cardiovascular therapeutics, and blood product transfusion in patients affected by type A lactic acidosis. Lactate concentration in peritoneal, pericardial, and synovial fluid can also be used as a diagnostic tool. Point of care analyzers such as the Lactate Pro, Lactate Scout, Accutrend, iSTAT, and Lactate Plus have been shown to be accurate lactate measurement instruments in small animal patients.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Topics in Companion Animal Medicine - Volume 31, Issue 1, March 2016, Pages 35–43
نویسندگان
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