کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2429727 | 1106518 | 2009 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Characterization of two isoforms of Japanese spiny lobster Panulirus japonicus defensin cDNA
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شناسی تکاملی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Characterization of two isoforms of Japanese spiny lobster Panulirus japonicus defensin cDNA Characterization of two isoforms of Japanese spiny lobster Panulirus japonicus defensin cDNA](/preview/png/2429727.png)
چکیده انگلیسی
Antimicrobial peptides (AMPs) are components of the innate immune responses that form the first line of host defense against pathogens. In this study, cDNAs of two new isoforms of defensin (designated PJD1 and PJD2) from a Japanese spiny lobster Panulirus japonicus haemocytes cDNA library were cloned and sequenced. PJD1 and PJD2 consist of 656 and 673 nucleotides encoding putative proteins of 66 and 64 amino acids, respectively. The isoforms share 74.2% amino acid identity. In a phylogenetic analysis, the peptides clustered with vertebrate defensins and were closely mostly related to chicken β-defensin. PJD1 and PJD2 were detected in all tissues examined including heart, nerves, intestine, haemocytes, gills and hepatopancreas.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Developmental & Comparative Immunology - Volume 33, Issue 4, April 2009, Pages 434–438
Journal: Developmental & Comparative Immunology - Volume 33, Issue 4, April 2009, Pages 434–438
نویسندگان
Duangjai Pisuttharachai, Motoshige Yasuike, Hideaki Aono, Yutaka Yano, Keisuke Murakami, Hidehiro Kondo, Takashi Aoki, Ikuo Hirono,