کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2433782 1106856 2006 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Evidence for melano-macrophage centres of teleost as evolutionary precursors of germinal centres of higher vertebrates: An immunohistochemical study
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم آبزیان
پیش نمایش صفحه اول مقاله
Evidence for melano-macrophage centres of teleost as evolutionary precursors of germinal centres of higher vertebrates: An immunohistochemical study
چکیده انگلیسی

The melano-macrophage centres (MMCs) of the haemolymphopoietic organs of teleost fish trap and retain antigens and are closely associated with immunoglobulin-secreting cells. The hypothesis that they are the phylogenetic precursors of the germinal centres of higher vertebrates has been questioned due to their apparent lack of organising cells. In this study the immunoreactivity of MMC cells from spleen and kidney of the teleosts Cyprinus carpio, Odontesthes bonariensis and Solea senegalensis to CNA-42, an antibody usually employed for labelling follicular dendritic cells of higher vertebrates was investigated. Free melano-macrophages and MMCs in the spleens of all three species were labelled by the antibody. This finding adds new evidence to the hypothesis that an evolutionary relationship exists between the MMCs of fish and the germinal centres of many birds and mammals.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Fish & Shellfish Immunology - Volume 21, Issue 4, October 2006, Pages 467–471
نویسندگان
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