کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2455351 1110511 2011 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Passive immunisation of post-weaned piglets using hyperimmune serum against experimental Haemophilus parasuis infection
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم دامی و جانورشناسی
پیش نمایش صفحه اول مقاله
Passive immunisation of post-weaned piglets using hyperimmune serum against experimental Haemophilus parasuis infection
چکیده انگلیسی

The protective role of hyperimmune serum in the prevention of Haemophilus parasuis infections in post-weaned piglets was assessed by experimental challenge. The hyperimmune serum was obtained from a pig vaccinated with a commercial vaccine against Glässer’s disease. Thirty-eight weaned piglets were divided into four groups: three groups were immunised intramuscularly with 10 ml of hyperimmune serum and one group consisted of unimmunised control animals. All piglets were subsequently infected intraperitoneally with H. parasuis serotype 5 at different times after immunisation. The use of hyperimmune serum provided the piglets with partial protection against experimental infection. The levels of protection indirectly depend on time between serum inoculation and challenge infection. The best protection of piglets against experimental infection was obtained in the group immunised 1 week before inoculation; the same group in which the highest levels of antibodies were detected at the time of challenge.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Research in Veterinary Science - Volume 91, Issue 2, October 2011, Pages 225–229
نویسندگان
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