کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2456451 | 1110542 | 2008 | 8 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Distribution of mast cell subtypes and immune cell populations in canine intestines: Evidence for age-related decline in T cells and macrophages and increase of IgA-positive plasma cells Distribution of mast cell subtypes and immune cell populations in canine intestines: Evidence for age-related decline in T cells and macrophages and increase of IgA-positive plasma cells](/preview/png/2456451.png)
The distribution and numbers of leucocytes and mast cells (MC) in the canine gastrointestinal tract of three different age groups was investigated immunhistochemically. In all age groups, CD3+ T cells were more prominent in the villus region than in the crypt areas without differences between intestinal segments, whereas macrophages were more randomly distributed. Kresylecht-violet and tryptase-positive MC were prominent in pericrypt regions with statistic significances. Chymase-bearing mast cells, IgA-, IgG- and IgM-containing cells did not show significant differences in their distribution but, except for IgG-positive cells, subjective trends with increasing numbers towards the crypts exist. The reasons for the distribution of T cells, macrophages, immunoglobulin-containing cells and mast cells are not clear. Lamina propria CD3+ T cells and macrophages significantly decreased whilst a significant increase of IgA-containing plasma cells with increasing age was found. For mast cell subtypes, IgG- and IgM-containing cells no significant changes in numbers with increasing age exist.
Journal: Research in Veterinary Science - Volume 84, Issue 1, February 2008, Pages 41–48