کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2507512 1117491 2014 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Cell microenvironment stimuli-responsive controlled-release delivery systems based on mesoporous silica nanoparticles
ترجمه فارسی عنوان
سیستم تحرک کنترل شده تحریک کننده سلول های میکرو محیطی مبتنی بر نانوذرات سیلیکا مزوپور است
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک دانش تغذیه
چکیده انگلیسی

To develop novel tumor cell microenvironment stimuli-responsive smart controlled-release delivery systems is one of the current common interests of materials science and clinical medicine. Meanwhile, mesoporous silica nanoparticles as a promising drug carrier have become the new area of interest in the field of biomedical application in recent years because of their unique characteristics and abilities to efficiently and specifically entrap cargo molecules. This review describes the more recent developments and achievements of mesoporous silica nanoparticles in drug delivery. In particular, we focus on the stimuli-responsive controlled-release systems that are able to respond to tumor cell environmental changes, such as pH, glucose, adenosine-5′-triphosphate (ATP), glutathione (GSH), and H2O2.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Food and Drug Analysis - Volume 22, Issue 1, March 2014, Pages 18–28
نویسندگان
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