Peptide based immunotherapy: A pivotal tool for allergy treatment

• Immunotherapy is a promising mode of allergy treatment.
• Immunotherapies with T-cell epitope peptides have safe and effective responses.
• Fcγ1–Fel d1 fusion protein suppresses cat allergy symptoms.
• CpG-Cry j2 induces anti-allergic effects in JCP.
• Egg allergen ovomucoid (Ovm) fusion protein reduces egg allergy.

Immunotherapies with T-cell epitope peptides have shown a promising impact over allergic diseases as a potential therapeutic tool in in vitro and in vivo conditions. It is recognized as an effective treatment with long lasting clinical effects and subsequent reduction of the allergic inflammatory reactions. In this review, we have summarized the role of peptide based immunotherapy and emphasis has been given to the recent advancement in pollen, cat, hymenoptera venom, and food allergy.