کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2541193 1122645 2011 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Regulation of adaptive immunity by the NLRP3 inflammasome
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ایمونولوژی
پیش نمایش صفحه اول مقاله
Regulation of adaptive immunity by the NLRP3 inflammasome
چکیده انگلیسی

It is well known that the innate immune system can induce and regulate the development of adaptive immunity. The NLRP3 inflammasome is a multiprotein complex that controls the caspase-1 activation step that is a pre-requisite for the maturation of interleukin (IL)-1β and IL-18. Recent findings showed that the NLRP3 inflammasome not only is an innate responder to pathogenic and danger signals, but also can affect the adaptive immune response. Here we review the role of NLRP3 inflammasome in regulating adaptive immunity.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Immunopharmacology - Volume 11, Issue 5, May 2011, Pages 549–554
نویسندگان
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