کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2541481 1122659 2009 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Serum adipsin levels in patients with seasonal allergic rhinitis: Preliminary data
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ایمونولوژی
پیش نمایش صفحه اول مقاله
Serum adipsin levels in patients with seasonal allergic rhinitis: Preliminary data
چکیده انگلیسی

BackgroundSeveral studies have outlined a possible relationship between adipokines and respiratory allergic diseases. However, there are no data about a role for adipsin in allergic rhinitis.ObjectiveThe aim of the study was to evaluate the serum adipsin levels in patients with seasonal allergic rhinitis (SAR), subdivided into two sub-groups: treated or not treated with sublingual immunotherapy (SLIT), and in a group of healthy controls.MethodsThe study included 110 subjects; i) 24 SLIT-treated SAR patients, ii) 62 untreated SAR patients, and iii) 24 normal subjects. All subjects were consecutively evaluated. A skin prick test and blood sampling for assessing serum adipsin levels were performed in all subjects.ResultsSerum adipsin was increased in SAR patients, even though significant only in males. There was also a significant positive association between adipsin and adiponectin.ConclusionThis preliminary study reports that adipsin serum levels may be increased in some SAR patients, but further functional studies should be performed.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Immunopharmacology - Volume 9, Issue 12, November 2009, Pages 1460–1463
نویسندگان
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