کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2542229 | 1122693 | 2006 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Detection, isolation and partial characterization of an immunostimulating glycoprotein from Rhodococcus fascians
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
ایمونولوژی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Detection, isolation and partial characterization of an immunostimulating glycoprotein from Rhodococcus fascians Detection, isolation and partial characterization of an immunostimulating glycoprotein from Rhodococcus fascians](/preview/png/2542229.png)
چکیده انگلیسی
In a search for novel immunostimulating substances we detected that culture supernatants of the gram-positive phytopathogenic bacterium, Rhodococcus fascians, were able to induce cytokine release (TNFα) from mouse peritoneal macrophages. Monoclonal antibodies were generated against the active principle, and were employed for its isolation and partial characterization as a high molecular (MW>100 kDa) glycoprotein. In addition, methods practicable for its biotechnological preparation and several ELISA variants for its determination were developed.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Immunopharmacology - Volume 6, Issue 9, September 2006, Pages 1441–1450
Journal: International Immunopharmacology - Volume 6, Issue 9, September 2006, Pages 1441–1450
نویسندگان
Günter Butschak, Uwe Karsten, Ute Schelhaas, Holger Ott, Andreas Emmendörffer, Bernd Niemeyer, Heike Helmholz, Steffen Goletz,