کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2572173 1561191 2016 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Evaluation of the deleterious health effects of consumption of repeatedly heated vegetable oil
ترجمه فارسی عنوان
بررسی اثرات نامطلوب سلامت مصرف روغن گیاهی مکرر گرما
کلمات کلیدی
روغن پخت و پز بطور مداوم گرم می شود ارزش پراکسید، استرس اکسیداتیو، پارامترهای هماتولوژیک،
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم محیط زیست بهداشت، سم شناسی و جهش زایی
چکیده انگلیسی
Consumption of repeatedly heated cooking oil (RHCO) has been a regular practice without knowing the harmful effects of use. The present study is based on the hypothesis that, heating of edible oils to their boiling points results in the formation of free radicals that cause oxidative stress and induce damage at the cellular and molecular levels. Peroxide value of heated oil, histopathological alterations, antioxidant enzyme levels and blood biochemistry were determined in Wistar rats treated with the RHCO. RHCO revealed higher peroxide value in comparison to oil that has been unheated or singly heated. Histopathological observation depicted significant damage in jejunum, colon and liver of animals that received oil heated repeatedly for 3 times. The altered antioxidant status reflects an adaptive response to oxidative stress. Alteration in the levels of these enzymes might be due to the formation of reactive oxygen species (ROS) through auto oxidation or enzyme catalyzed oxidation of electrophilic components within RHCO. Analysis of blood samples revealed elevated levels of glucose, creatinine and cholesterol with declined levels of protein and albumin in repeatedly heated cooking oil group. Hematological parameters did not reveal any statistically significant difference between treated and control groups. Results of the present study confirm that the thermal oxidation of cooking oil generates free radicals and dietary consumption of such oil results in detrimental health effects.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Toxicology Reports - Volume 3, 2016, Pages 636-643
نویسندگان
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