کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2573202 1129363 2009 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Liposomes and nanoparticles: nanosized vehicles for drug delivery in cancer
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب سلولی و مولکولی
پیش نمایش صفحه اول مقاله
Liposomes and nanoparticles: nanosized vehicles for drug delivery in cancer
چکیده انگلیسی

Nanoscale drug delivery systems using liposomes and nanoparticles are emerging technologies for the rational delivery of chemotherapeutic drugs in the treatment of cancer. Their use offers improved pharmacokinetic properties, controlled and sustained release of drugs and, more importantly, lower systemic toxicity. The commercial availability of liposomal Doxil® and albumin-nanoparticle-based Abraxane® has focused attention on this innovative and exciting field. Recent advances in liposome technology offer better treatment of multidrug-resistant cancers and lower cardiotoxicity. Nanoparticles offer increased precision in chemotherapeutic targeting of prostate cancer and new avenues for the treatment of breast cancer. Here we review current knowledge on the two technologies and their potential applications to cancer treatment.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: - Volume 30, Issue 11, November 2009, Pages 592–599
نویسندگان
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