The impact of Triton WR-1339 induced hyperlipidemia on the effects of benzo(a)pyrene or guaiacol on α- and γ-tocopherol pools and selected markers of pro-/antioxidative balance in rat plasma and erythrocytes

► The impact of hyperlipidemia induced by Triton WR-1339 on co-oxygenation effects of benzo(a)pyrene (BaP) or guaiacol was studied in rat. ► Tocopherol pools and pro-/antioxidative balance markers in blood were measured. ► In normolipemic groups malondialdehyde (MDA) increased and erythrocyte tocopherol decrease after BaP or guaiacol short-lasting treatment. ► Pro-oxidative effects of BaP and guaiacol were not increased in hyperlipemic animals.