کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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2588962 | 1561937 | 2007 | 7 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Outbreak detection and secondary prevention of Legionnaires’ disease: A national approach Outbreak detection and secondary prevention of Legionnaires’ disease: A national approach](/preview/png/2588962.png)
BackgroundTo stop a possible outbreak of Legionnaires’ disease (LD) at an early stage an outbreak detection programme was installed in The Netherlands.MethodsThe programme consisted of sampling and controlling of potential sources to which LD patients had been exposed during their incubation period. Potential sources were considered to be true sources of infection if two or more LD patients (cluster) had visited them, or if available patients’ isolates and environmental Legionella spp. were indistinguishable by amplified fragment length polymorphism genotyping.ResultsRapid sampling and genotyping as well as cluster recognition helped to target control measures. Despite these measures, two small outbreaks were only stopped after renewal of the water system. The combination of genotyping and cluster recognition lead to 29 of 190 (15%) patient–source associations.ConclusionSystematic sampling and cluster recognition can contribute to outbreak detection and lead to cost-effective secondary prevention of Legionnaires’ disease.
Journal: International Journal of Hygiene and Environmental Health - Volume 210, Issue 1, 13 February 2007, Pages 1–7