کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2589768 1131705 2012 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The neurotoxic potential of engineered nanomaterials
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم محیط زیست بهداشت، سم شناسی و جهش زایی
پیش نمایش صفحه اول مقاله
The neurotoxic potential of engineered nanomaterials
چکیده انگلیسی

The expanding development and production of engineered nanomaterials (ENMs) have diverse and far-reaching potential benefits in consumer products, food, drugs, medical devices and for enhancing environmental cleanup and remediation. The knowledge of potential implications of ENMs, including the potential for inadvertent exposures and adverse neurotoxic consequences, is lagging behind their development. A potential risk for neurotoxicity arises if exposure leads to systemic absorption and distribution to the nervous system. This paper is the summary of a symposium entitled Neurotoxicity Potential of Engineered Nanomaterials presented at the 2011 Xi’an International Neurotoxicology Conference held June 5–9 in Xi’an China. The following topics were featured in the symposium: the toxicokinetics of engineered nanomaterials; differential uptake of nanoceria in brain and peripheral organs; translocation into the brain and potential damage following nanoparticle exposure; and the retina as a potential site of nanomaterial phototoxicity. Each of these topics is discussed fully in sections of the manuscript. The promising benefits of ENM technology can be best realized if the potential risks are first understood and then minimized in product and system designs.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: NeuroToxicology - Volume 33, Issue 4, August 2012, Pages 902–910
نویسندگان
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