De l'inflammation des petites voies aériennes à la dyspnée d'effort dans la bronchopneumopathie chronique obstructive

Dynamic hyperinflation is a major determinant of dyspnoea in chronic obstructive pulmonary disease (COPD). Thus, it represents a major target for treatments. This review discusses the ventilatory consequences of small airways disease, which is related to inflammatory processes and occurs early in the natural history of COPD.