کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2719030 | 1145574 | 2013 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
BioCASTÂ : le Bio-observatoire national du cancer bronchiques chez les patients non fumeurs (IFCT1002)
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
کاردیولوژی و پزشکی قلب و عروق
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چکیده انگلیسی
Around 5 to 25% of lung cancer worldwide occurs in lifelong non-smokers (less than 100Â cigarettes in lifetime). Lung cancer in never smokers (LCINS) shows many clinical, epidemiological and molecular differences compared to those related to tobacco. It is therefore often considered as a separate entity. LCINS is also a good model for the study of lung cancer risk factors and tumoral mutation profiles (usually more common and specific). However, most data has come from retrospective studies and/or from Asian populations, although this disease shows high geographic lability. The BioCAST/IFCT-1002 is a national, multicentric, prospective study promoted by the French intergroup IFCT. The first objective is to describe the clinical and molecular epidemiology of LCINS in a French population. Detailed data (including exposure to many risk factors) are collected directly from the patient through a standardized questionnaire completed during a telephone interview. All patients also undergo blood sampling for the analysis of genomic polymorphisms and the characterization of epigenetic anomalies. BioCAST hopes to provide concrete answers for clinicians and patients about this entity.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Revue des Maladies Respiratoires - Volume 30, Issue 7, September 2013, Pages 576-583
Journal: Revue des Maladies Respiratoires - Volume 30, Issue 7, September 2013, Pages 576-583
نویسندگان
S. Couraud, S. Labonne, P. Missy, F. Morin, Q. Tran, A. Deroy, B. Milleron, H. Blanché, G. Zalcman, P.-J. Souquet, les membres du Groupe de travail « non-fumeurs de l'IFCT » les membres du Groupe de travail « non-fumeurs de l'IFCT »,