کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2753083 1149611 2011 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Role of Computed Tomography Fluoroscopy–Guided Cutting Needle Biopsy of Lung Lesions After Transbronchial Examination Resulting in Negative Diagnosis
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیهوشی و پزشکی درد
پیش نمایش صفحه اول مقاله
Role of Computed Tomography Fluoroscopy–Guided Cutting Needle Biopsy of Lung Lesions After Transbronchial Examination Resulting in Negative Diagnosis
چکیده انگلیسی

Introduction: Computed tomography (CT)–guided lung biopsy is occasionally used for the lesions that were diagnosed as nonmalignant by transbronchial examination despite the fact that other clinical data suggested those as malignant. The purpose of this study is to evaluate the outcomes of CT fluoroscopy–guided cutting needle biopsy of lung lesions after transbronchial examination resulting in negative diagnosis.Patients and MethodsWe retrospectively evaluated the outcomes of CT fluoroscopy–guided lung biopsy for 351 lesions (mean size, 2.8 cm) that were found to be nonmalignant by transbronchial examination. Diagnostic yield, including sensitivity and specificity for the diagnosis of malignancy, positive predictive value (PPV), negative predictive value (NPV), and accuracy were calculated. Various variables were analyzed to determine the factors for diagnostic failure.ResultsThe biopsy result was nondiagnostic, true-positive, true-negative, false-positive, or false-negative for 2, 262, 70, 0, or 17 lesions, respectively. Thus, the sensitivity, specificity, PPV, NPV, and accuracy of CT fluoroscopy–guided cutting needle biopsy was found to be 93% (262/281), 100% (70/70), 100% (262/262), 80% (70/87), and 94% (332/351), respectively. There was no significant risk factor for diagnostic failure.ConclusionComputed tomography fluoroscopy–guided cutting needle lung biopsy is a useful technique to correct or confirm negative diagnosis by transbronchial examination.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Clinical Lung Cancer - Volume 12, Issue 1, January 2011, Pages 51–55
نویسندگان
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