کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2759541 1150156 2013 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Simplified Clinical Risk Score to Predict Acute Kidney Injury After Aortic Surgery
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیهوشی و پزشکی درد
پیش نمایش صفحه اول مقاله
Simplified Clinical Risk Score to Predict Acute Kidney Injury After Aortic Surgery
چکیده انگلیسی

ObjectiveThe authors identified risk factors for acute kidney injury (AKI) defined by risk, injury, failure, loss, end-stage (RIFLE) criteria after aortic surgery with cardiopulmonary bypass and constructed a simplified risk score for the prediction of AKI.DesignRetrospective and observational.SettingSingle large university hospital.ParticipantsPatients (737) who underwent aortic surgery with cardiopulmonary bypass between 1997 and 2010.Main ResultsMultivariate logistic regression analysis was used to evaluate risk factors. A scoring model was developed in a randomly selected derivation cohort (n = 417), and was validated on the remaining patients. The scoring model was developed with a score based on regression β-coefficient, and was compared with previous indices as measured by the area under the receiver operating characteristic curve (AUC). The incidence of AKI was 29.0%, and 5.8% required renal replacement therapy. Independent risk factors for AKI were age older than 60 years, preoperative glomerular filtration rate <60 mL/min/1.73 m2, left ventricular ejection fraction <55%, operation time >7 hours, intraoperative urine output <0.5 mL/kg/h, and intraoperative furosemide use. The authors made a score by weighting them at 1 point each. The risk score was valid in predicting AKI, and the AUC was 0.74 [95% confidence interval (CI): 0.69 to 0.79], which was similar to that in the validation cohort: 0.74 (95% CI: 0.69 to 0.80; p = 0.97). The risk-scoring model showed a better performance compared with previously reported indices.ConclusionsThe model would provide a simplified clinical score stratifying the risk of postoperative AKI in patients undergoing aortic surgery.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Cardiothoracic and Vascular Anesthesia - Volume 27, Issue 6, December 2013, Pages 1158–1166
نویسندگان
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