Effect of Isoflurane on Echocardiographic Left-Ventricular Relaxation Indices in Patients With Diastolic Dysfunction Due to Concentric Hypertrophy and Ischemic Heart Disease

Conclusion: Isoflurane did not exacerbate diastolic dysfunction in patients with concentric hypertrophy and ischemic heart disease. In contrast, isoflurane led to a “normalization” of the relaxation pattern that was attributed to a reduction in left-ventricular loading conditions.