کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2767540 | 1151143 | 2006 | 16 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
The Role of the Dorsal Root Ganglion in Cervical Radicular Pain: Diagnosis, Pathophysiology, and Rationale for Treatment
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
بیهوشی و پزشکی درد
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چکیده انگلیسی
Cervical radicular pain affects 83 per 100,000 adults annually. Diagnosis by means of physical examination, imaging, and electrophysiological studies is characterized by high specificity but low sensitivity. In this review, we focus on the role of the dorsal root ganglion and those treatment modalities that aim at pathophysiological mechanisms occurring after injury to the dorsal root ganglion. Cervical nerve injury initiates multiple events that lead to changes in nerve function and result in spontaneous firing at the dorsal root ganglion. Among these, inflammation and changes in ion-channel function play a pivotal role. Although many treatment modalities are described in the literature, the available evidence for efficacy does not allow us to formulate definitive conclusions on the optimal therapy. A lack of evidence is reported for cervical spine surgery. Interlaminar epidural steroid administration and radiofrequency techniques adjacent to the cervical dorsal root ganglion have the highest, but still weak recommendations.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Regional Anesthesia and Pain Medicine - Volume 31, Issue 2, March 2006, Pages 152-167
Journal: Regional Anesthesia and Pain Medicine - Volume 31, Issue 2, March 2006, Pages 152-167
نویسندگان
Jan M.D., Ph.D., Donal M.D., Elbert A.J. Ph.D., Marcel E. M.D., Ph.D., Jacob M.D., Ph.D., Martin H. M.D., Ph.D., Maarten M.D., Ph.D.,