کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2793604 1155160 2007 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A Balance of Lipid-Sensing Mechanisms in the Brain and Liver
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی علوم غدد
پیش نمایش صفحه اول مقاله
A Balance of Lipid-Sensing Mechanisms in the Brain and Liver
چکیده انگلیسی

Recent work has cast a spotlight on the brain as a nutrient-sensing organ that regulates the body's metabolic processes. Here we discuss the physiological and molecular mechanisms of brain lipid sensing and compare these mechanisms to liver lipid sensing. A direct comparison between the lipid-sensing mechanisms in the brain and liver reveals similar biochemical/molecular but opposing physiological mechanisms in operation. We propose that an imbalance between the lipid-sensing mechanisms in the brain and liver may contribute to obesity-associated type 2 diabetes.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: - Volume 6, Issue 2, 8 August 2007, Pages 99–104
نویسندگان
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