Cardiorespiratory fitness and mortality in diabetic men with and without cardiovascular disease

We assessed joint associations of cardiorespiratory fitness and diabetes, cardiovascular disease (CVD), or both with all-cause mortality. High-fitness eliminated mortality risk in diabetes (P < 0.001) and halved risk of death in diabetes/CVD (P < 0.001). Fitness was a potent effect modifier in the association of diabetes and CVD to mortality.