Elevation of serum adiponectin and CD146 levels in diabetic nephropathy

These results indicate that serum adiponectin levels seem to reduce in the diabetic patients, and finally increase in end stage of diabetic nephropathy. In contrast, serum CD146 may closely associate with development of micro- and macrovascular complications in diabetic patients. Further study is required to elucidate the exact role of adiponectin and CD146 in the development of vascular complication in end stage of diabetic nephropathy.