کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2809656 1158068 2008 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Alginate reduces the increased uptake of cholesterol and glucose in overweight male subjects: a pilot study
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی علوم غدد
پیش نمایش صفحه اول مقاله
Alginate reduces the increased uptake of cholesterol and glucose in overweight male subjects: a pilot study
چکیده انگلیسی

Dietary fibers are of particular interest in the prevention and management of obesity and consequent pathologies. Among the proposed mechanisms of action of fiber is the modulation of nutrient uptake from the small intestine. We have used a crossover study design in human subjects to monitor the uptake of glucose, cholesterol, and triacylglycerols in human subjects with normal and high body mass index. Our data demonstrate that uptakes of glucose, triacylglycerols, and cholesterol are all increased with increasing body fat. We demonstrate that treatment with a 1.5-g dose of a strong-gelling alginate may restore uptake of cholesterol and glucose to the levels of healthy subjects. These data indicate a potential therapeutic application of gelling fibers.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Nutrition Research - Volume 28, Issue 8, August 2008, Pages 501–505
نویسندگان
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