کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2810873 1158489 2007 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Flaws in the theory of predictive adaptive responses
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی علوم غدد
پیش نمایش صفحه اول مقاله
Flaws in the theory of predictive adaptive responses
چکیده انگلیسی

Human foetuses have been proposed to make ‘predictive adaptive responses’ during pregnancy, to adapt metabolic profile in anticipation of conditions expected in adulthood. Predictive adaptive responses are invoked in particular to explain associations between early-life experience and risk of the metabolic syndrome, although the concept is problematic on theoretical grounds and fits poorly with empirical data. In ecosystems, as in economics, the future cannot be predicted with confidence. It is likely to be the case that human offspring look not to the future but back to the past, and align their developmental trajectory with maternal phenotype, the key factor in determining their nutritional supply. This debate has important implications, potentially offering a robust theoretical basis for designing public health interventions and guiding the nutritional management of individual infants.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: - Volume 18, Issue 9, November 2007, Pages 331–337
نویسندگان
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