The origin of dengue viruses caused the DF outbreak in Guangdong province, China, in 2006

Phylogenetic analysis suggested that the DENV1 strains isolated in the DF outbreak in Guangdong province in 2006 were likely to be imported from Southeast Asian. Specifically, viruses isolated from Shantou and Chaozhou were imported from Singapore; viruses isolated from Guangzhou, Yangjiang, and Foshan were imported from Thailand/Vietnam. Therefore, importation of DENV1 from Southeast Asia was an important contributory factor of the 2006 DF outbreak in Guangdong province.

► DENV1 strains isolated in Guangdong province in 2006 were grouped into 3 clades.
► These strains were likely to be imported from Southeast Asian.
► Importation of DENV1 was an important contributory factor of the 2006 DF outbreak.