Evolutionary genomics of Glossina morsitans immune-related CLIP domain serine proteases and serine protease inhibitors

▶ 11 ORFs encoding CLIP domains serine proteases and 10 serine protease inhibitors (SERPINS). ▶ Amino acid content of the G. morsitans serpin reactive site (RSL) suggest an inhibitory mechanism. ▶ Absence of gene expansion in G. morsitans CLIP-domain serine protease and SERPIN families. ▶ Different scissile bond residues in D. melanogaster and G. morsitans serpin4 isoforms.