کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2828336 | 1162488 | 2006 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Helicobacter pylori infection and HFE hemochromatosis
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موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شناسی مولکولی
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چکیده انگلیسی
Helicobacter pylori infections are associated with iron deficiency, even in the absence of bleeding. To determine whether H. pylori infection plays a role in modifying the phenotype of patients homozygous for the c.845 G>A (C282Y) mutation of the HFE gene we studied 79 homozygous women and 76 homozygous men, comparing the pretreatment hemoglobin, MCV, serum ferritin, transferrin saturation of those who were seropositive and seronegative for H. pylori. No difference between seropositive and seronegative homozytoes was found. There was also no difference between seropositive and seronegative control subjects. We also compared the total iron of 56 of the male and 32 of the female homozygotes as determined by serial phlebotomy. No significant difference was found.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Blood Cells, Molecules, and Diseases - Volume 37, Issue 3, NovemberâDecember 2006, Pages 188-191
Journal: Blood Cells, Molecules, and Diseases - Volume 37, Issue 3, NovemberâDecember 2006, Pages 188-191
نویسندگان
Ernest Beutler, Terri Gelbart,