کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2828336 1162488 2006 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Helicobacter pylori infection and HFE hemochromatosis
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شناسی مولکولی
پیش نمایش صفحه اول مقاله
Helicobacter pylori infection and HFE hemochromatosis
چکیده انگلیسی
Helicobacter pylori infections are associated with iron deficiency, even in the absence of bleeding. To determine whether H. pylori infection plays a role in modifying the phenotype of patients homozygous for the c.845 G>A (C282Y) mutation of the HFE gene we studied 79 homozygous women and 76 homozygous men, comparing the pretreatment hemoglobin, MCV, serum ferritin, transferrin saturation of those who were seropositive and seronegative for H. pylori. No difference between seropositive and seronegative homozytoes was found. There was also no difference between seropositive and seronegative control subjects. We also compared the total iron of 56 of the male and 32 of the female homozygotes as determined by serial phlebotomy. No significant difference was found.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Blood Cells, Molecules, and Diseases - Volume 37, Issue 3, November–December 2006, Pages 188-191
نویسندگان
, ,