La activación de receptor activado por proliferadores peroxisómicos β/δ mejora la resistencia a insulina inducida por IL-6 en células hepáticas

These findings indicate that the PPARβ/δ agonist GW501516 prevents IL-6-induced STAT3 activation by inhibiting ERK1/2 phosphorylation. These effects of GW501516 may contribute to the prevention of cytokine-induced insulin resistance in hepatic cells.