Expresión de la lisil oxidasa (LOX) en la pared vascular: mecanismos implicados en la regulación de la LOX por lipoproteínas de baja densidad

LOX downregulation by LDL requires lipoprotein lysosomal processing. Both LOX regulation by lipoproteins and its strong endothelial expression support the role of this enzyme in endothelial dysfunction triggered by hypercholesterolemia and suggest that it contributes to the atherosclerotic process.