Dose Escalation of Once Weekly Oral Vinorelbine Concurrent With Weekly Split Dose Hypofractionated Chest Radiation for Palliation of Advanced Non-Small Cell Lung Cancer: A Phase I/II Study

Weekly, hypofractionated chest radiation is well tolerated and can be administered safely concurrently with vinorelbine at systemic doses. This simplified, convenient regimen could benefit patients in need for both local and systemic palliation.