Effect of Angiotensin Converting Enzyme Inhibitors and Angiotensin Receptor Blockers on Serum Potassium Levels and Renal Function in Ambulatory Outpatients: Risk Factors Analysis

Although generally safe, ACEinh/ARB poses a small risk for hyperkalemia in patients with reduced GFR. Because the propensity is incremental with declining GFR, these agents should be used with caution in advancing stages of CKD. Presence of diabetes does not affect the development of hyperkalemia.