Passive leg raising induced brachial artery dilation: Is an old technique a simpler method to measure endothelial function?

BAD occurs in response to PLR and is proportional to FMD, although the magnitude of PLR-BAD is less than half that of FMD. It appears to occur by the same endothelial dependent mechanism as FMD. PLR-BAD may be used as a surrogate measure of FMD to evaluate vascular function, and has the advantage of being simpler to perform.