کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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2893168 | 1172405 | 2010 | 5 صفحه PDF | دانلود رایگان |

ObjectiveRecently, the technique of high-resolution magnetic resonance imaging (HR-MRI) has been developed to depict intracranial artery wall. We aimed to compare the vessel wall properties between symptomatic and asymptomatic atherosclerotic middle cerebral arteries (MCA) using HR-MRI.MethodsWe studied 26 patients with symptomatic and 35 patients with asymptomatic MCA stenosis. Routine cranial MRI, magnetic resonance angiography and HR-MRI were performed on each patient. The cross-sectional images of MCA wall on HR-MRI were compared between the two groups.ResultsThe degree of MCA stenosis was similar between the two groups (67.9% vs 63.9%, P = 0.327). On HR-MRI, eccentric plaques were observed in 26 (100%) symptomatic and 28 (80%) asymptomatic stenosis. In the remaining seven (20%) asymptomatic stenosis, only constrictive remodeling (vessel shrinkage) was observed. Compared with the asymptomatic group, symptomatic MCA stenosis had a larger wall area (P < 0.001), greater remodeling ratio (P < 0.001), higher prevalence of expansive remodeling (outward expansion of the vessel wall) (P = 0.003) and lower prevalence of constrictive remodeling (P = 0.008).ConclusionsDifferent vessel wall properties on HR-MRI were observed between symptomatic and asymptomatic MCA stenosis. Further prospective studies are required to investigate whether HR-MRI is a helpful tool in stratifying stroke risk in patients with MCA atherosclerotic disease.
Journal: Atherosclerosis - Volume 212, Issue 2, October 2010, Pages 507–511