کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2894449 1172435 2007 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
c-Reactive protein and the metabolic syndrome in older Chinese: Guangzhou Biobank Cohort Study
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی کاردیولوژی و پزشکی قلب و عروق
پیش نمایش صفحه اول مقاله
c-Reactive protein and the metabolic syndrome in older Chinese: Guangzhou Biobank Cohort Study
چکیده انگلیسی

ObjectiveTo examine the association between serum c-reactive protein (CRP) concentration and the metabolic syndrome (MS) using the International Diabetes Federation Metabolic Syndrome Guidelines (April, 2005) definition in an older Chinese population.MethodsThree thousand and fourteen men and 7275 women aged 50–85 years were recruited and received a full medical check-up including measurement of blood pressure, obesity indices, fasting total, LDL-, HDL-cholesterol, triglycerides, glucose and c-reactive protein. Data describing socioeconomic and lifestyle factors was also collected.ResultsVascular risk factors including waist circumference, weight gain and waist gain since the age of 18, body mass index, waist–hip-ratio, triglyceride, HDL-cholesterol, and systolic and diastolic blood pressures were positively associated with CRP in both men and women (p from <0.001 to 0.016). Compared to those without MS components, adjusted odds ratios for having elevated CRP increased in those with the MS or its components compared those without MS or components (all p < 0.001), except for the low HDL-cholesterol in both genders and raised fasting glucose in men. Similarly, the risk of elevated CRP increased with escalating MS components even after adjustment of a range of potential confounders.ConclusionsThere is a strong relationship between CRP and the constellation of MS components and associated vascular risk in this older Chinese population.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Atherosclerosis - Volume 194, Issue 2, October 2007, Pages 483–489
نویسندگان
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