کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2902528 1173374 2009 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The Effects of Flexible Bronchoscopy on Mechanical Ventilation in a Pediatric Lung Model
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی کاردیولوژی و پزشکی قلب و عروق
پیش نمایش صفحه اول مقاله
The Effects of Flexible Bronchoscopy on Mechanical Ventilation in a Pediatric Lung Model
چکیده انگلیسی

BackgroundFlexible bronchoscopy performed through endotracheal tubes (ETTs) in children receiving mechanical ventilation can significantly impact ventilation, but the magnitude of this impact has not been established. We used a lung model to simulate mechanical ventilation in a range of child sizes in order to determine how the insertion of pediatric flexible bronchoscopes into ETTs alters ventilatory parameters, especially tidal volume (Vt) and peak inspiratory pressure (PIP), in both healthy and diseased lungs.MethodsWe simulated five child sizes based on weight, and evaluated 22 bronchoscope/ETT combinations, first in pressure control (PC) ventilation mode and then in volume control (VC) ventilation mode. The combinations ranged from the 2.2-mm (bronchoscope outer diameter)/3.0-mm (ETT inner diameter) to 5.0-mm bronchoscope/8.0-mm ETT. The primary outcome measures were decrease in Vt after bronchoscope insertion during PC ventilation and increase in PIP during VC ventilation.ResultsIn the PC ventilator mode, Vt decreased by > 50% with nine of the combinations, while during VC ventilation, PIP increased by ≥ 20 cm H2O with seven combinations. The 2.2-mm bronchoscope/3.0-mm ETT, 2.8-mm bronchoscope/5.0-mm ETT, and 3.6-mm bronchoscope/5.0-mm ETT combinations severely impaired ventilation, while the 3.6-mm bronchoscope/4.5-mm ETT, 5.0-mm bronchoscope/6.5-mm ETT, and 5.0-mm bronchoscope/7.0-mm ETT combinations were incompatible with adequate ventilation.ConclusionsThe insertion of bronchoscopes into ETTs can lead to clinically relevant decreases in Vt when in the PC ventilator mode and large increases in PIP during VC ventilation. The minimum bronchoscope/ETT diameter difference required to maintain adequate ventilation increases with child size.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Chest - Volume 135, Issue 1, January 2009, Pages 33–40
نویسندگان
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