کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2923231 1175866 2010 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Genome-wide association studies in cardiac electrophysiology: Recent discoveries and implications for clinical practice
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی کاردیولوژی و پزشکی قلب و عروق
پیش نمایش صفحه اول مقاله
Genome-wide association studies in cardiac electrophysiology: Recent discoveries and implications for clinical practice
چکیده انگلیسی

Genome-wide association studies have been increasingly used to study the genetics of complex human diseases. Within the field of cardiac electrophysiology, this technique has been applied to conditions such as atrial fibrillation, and several electrocardiographic parameters including the QT interval. While these studies have identified multiple genomic regions associated with each trait, questions remain, including the best way to explore the pathophysiology of each association and the potential for clinical utility. This review will summarize recent genome-wide association study results within cardiac electrophysiology and discuss their broader implications in basic science and clinical medicine.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Heart Rhythm - Volume 7, Issue 8, August 2010, Pages 1141–1148
نویسندگان
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