کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2923867 1175888 2008 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Left atrial function and scar after catheter ablation of atrial fibrillation
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی کاردیولوژی و پزشکی قلب و عروق
پیش نمایش صفحه اول مقاله
Left atrial function and scar after catheter ablation of atrial fibrillation
چکیده انگلیسی

BackgroundCatheter ablation of atrial fibrillation (AF) involves extensive radiofrequency ablation (RFA) of the left atrium (LA) around the pulmonary veins. The effect of this therapy on LA function is not fully characterized.ObjectiveThe purpose of this study was to determine whether catheter ablation of AF is associated with a change in LA function.MethodsLA and right atrial (RA) systolic function was assessed in 33 consecutive patients with paroxysmal or persistent AF referred for ablation using cardiovascular magnetic resonance (CMR) imaging. Steady-state free precession ECG cine CMR imaging was performed before and after (mean 48 days) AF ablation. All patients underwent circumferential pulmonary vein isolation using an 8-mm tip RFA catheter. High spatial resolution late gadolinium enhancement CMR images of LA scar were obtained in 16 patients.ResultsMaximum LA volume decreased by 15% (P <.001), and LA ejection fraction decreased by 14% (P <.001) after AF ablation. Maximum RA volume decreased by 13% (P = .018), but RA ejection fraction increased by 5% (P = .008). Mean LA scar volume was 8.1 ± 3.7 mL. A linear correlation was observed between change in LA ejection fraction and scar volume (r = −0.75, P <.001).ConclusionCatheter ablation of AF is associated with decreased LA size and reduced atrial systolic function. This change strongly correlates with the volume of LA scar. This finding may have implications for postprocedural thromboembolic risk and for procedures involving more extensive RFA.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Heart Rhythm - Volume 5, Issue 5, May 2008, Pages 656–662
نویسندگان
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