Efectos de la inhibición selectiva y no selectiva de la ciclooxigenasa en la vasodilatación dependiente de óxido nítrico y prostaciclina en pacientes hipertensos

These results suggest that the acute vasodilation induced by captopril is COX-1 dependent and the excess of cardiovascular risk of COX-2 inhibitors may be decreased by concomitant administration of ACE-inhibitors in hypertensive patients.