کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2944276 1577105 2014 12 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Coronary Artery Calcification : Pathogenesis and Prognostic Implications
ترجمه فارسی عنوان
کلسیفیکسیون عروق کرونر: پاتوژنز و پیامدهای پیش آگهی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی کاردیولوژی و پزشکی قلب و عروق
چکیده انگلیسی

Coronary artery calcification (CAC) is a risk factor for adverse outcomes in the general population and in patients with coronary artery disease. The pathogenesis of CAC and bone formation share common pathways, and risk factors have been identified that contribute to the initiation and progression of CAC. Efforts to control CAC with medical therapy have not been successful. Event-free survival is also reduced in patients with coronary calcification after both percutaneous coronary intervention (PCI) and bypass graft surgery. Although drug-eluting stents and devices for plaque modification have modestly improved outcomes in calcified vessels, adverse event rates are still high. Innovative pharmacologic and device-based approaches are needed to improve the poor prognosis of patients with CAC.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of the American College of Cardiology - Volume 63, Issue 17, 6 May 2014, Pages 1703–1714
نویسندگان
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