کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2962475 1178431 2007 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Clinical Efficacy of Surgical Heart Failure Therapy by Ventricular Restoration and Restrictive Mitral Annuloplasty
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی کاردیولوژی و پزشکی قلب و عروق
پیش نمایش صفحه اول مقاله
Clinical Efficacy of Surgical Heart Failure Therapy by Ventricular Restoration and Restrictive Mitral Annuloplasty
چکیده انگلیسی

BackgroundTreatment of heart failure by advanced surgical procedures such as ventricular restoration (SVR) and restrictive mitral annuloplasty (RMA) is increasingly applied. We studied clinical efficacy of heart failure surgery in patients with severe heart failure.Methods and ResultsThirty-three patients (New York Heart Association (NYHA) class III/IV, left ventricular ejection fraction ≤35%) were included. Patients with moderate to severe mitral regurgitation underwent RMA (85%) and patients with anteroseptal aneurysm underwent SVR (52%). A combined procedure was performed in 12 patients, and additional coronary artery bypass grafting in 27 patients. Clinical and echocardiographic parameters were assessed at baseline and 6 months after surgery. Operative mortality was 3% (n = 1), in-hospital mortality was 9% (n = 3), and there was no late mortality. All clinical parameters were significantly improved at 6 months' follow-up (P < .001); NYHA class improved from 3.4 ± 0.5 to 1.5 ± 0.5, Quality-of-life score improved from 44 ± 22 to 16 ± 12, and 6-minute walking distance increased from 248 ± 134 m to 422 ± 113 m. Left ventricular end-diastolic volume decreased from 107 ± 32 to 80 ± 20 mL/m2 (P < .001) and end-systolic volume decreased from 78 ± 32 to 53 ± 15 mL/m2 (P < .001), whereas ejection fraction improved from 29 ± 9 to 35 ± 7% (P < .01).ConclusionsSurgical treatment of severe heart failure by SVR or RMA was associated with 12% mortality at 6 months. Surviving patients showed highly significant functional and clinical improvements.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Cardiac Failure - Volume 13, Issue 3, April 2007, Pages 178–183
نویسندگان
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