کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2963238 1178546 2012 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Non-obstructive low attenuation coronary plaque predicts three-year acute coronary syndrome events in patients with hypertension: Multidetector computed tomographic study
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی کاردیولوژی و پزشکی قلب و عروق
پیش نمایش صفحه اول مقاله
Non-obstructive low attenuation coronary plaque predicts three-year acute coronary syndrome events in patients with hypertension: Multidetector computed tomographic study
چکیده انگلیسی

SummaryBackgroundArterial hypertension is an established risk factor for acute coronary syndrome (ACS). Multidetector computed tomography (MDCT) is an accurate and less invasive technique for assessment of the degree of coronary artery luminal narrowing and characterization of coronary atherosclerosis. We therefore aimed to investigate the predictive power of MDCT for future ACS events and compared with traditional parameters in patients with hypertension.MethodsOne hundred and thirty-four patients (93 men, mean age 70 ± 11 years) with hypertension underwent MDCT for evaluation of coronary artery disease. MDCT analysis focused on the presence of plaques, the degree of stenosis, and the plaque characteristics. Traditional parameters included Framingham risk score, carotid intima-media thickness, and left ventricular mass index.ResultsDuring a mean follow-up of 39 ± 10 months, ACS events occurred in 10 patients, including myocardial infarction (n = 3) and unstable angina (n = 7). Multivariate analysis identified total number of low attenuation plaques as an independent predictor of ACS events (p < 0.001).ConclusionWe demonstrated that non-obstructive low attenuation coronary plaques on MDCT predicted more accurately future ACS events in patients with hypertension than traditional parameters.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Cardiology - Volume 59, Issue 2, March 2012, Pages 167–175
نویسندگان
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